Oxandrolone appears to offer less hepatic stress than other c-17 alpha alkylated steroids. The manufacturer identifies oxandrolone as a steroid that is not extensively metabolized by the liver like other 17-alpha alkylated orals, which may be a factor in its reduced hepatotoxicity. This is evidenced by the fact that more than a third of the compound is still intact when excreted in the urine. 405 Another study comparing the effects of oxandrolone to other alkylated agents including methyltestosterone, norethandrolone, fluoxymesterone, and methandriol demonstrated that oxandrolone causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention of the agents tested. 406 20 mg of oxandrolone produced 72% less BSP retention than an equal dosage of fluoxymesterone,which is a considerable difference being that they are both 17-alpha alkylated.
Since Oxandrolone (Anavar) is less harmful and slightly affecting steroids, males are recommended to take noticeably higher dosages in order to achieve their desired goals and visible advantages. It is recommended for males that they must take 50 mg of this steroid every day. Some athletes who perform extensive training can increase the dosage to 80 mg every day but with strict precautions and proper consultation from the doctors. Since females are comparatively more vulnerable so they are recommended to take the maximum dose of 10mg every day and only 20mg of oxandrolone in each day. If the dosage exceeds from the limit then they might face some severe consequences. The time period of using Anavar for males and females are quite longer than any of the other anabolic steroids as they can take this steroid for almost 8 weeks.
The original brand name of oxandrolone was Anavar, which was marketed in the United States and the Netherlands .   This product was eventually discontinued and replaced in the United States with a new product named Oxandrin, which is the sole remaining brand name for oxandrolone in the United States.   Oxandrolone has also been sold under the brand names Antitriol ( Spain ), Anatrophill ( France ), Lipidex ( Brazil ), Lonavar ( Argentina , Australia , Italy ), Protivar, and Vasorome ( Japan ) among others.     Additional brand names exist for products that are manufactured for the steroid black market.