The common side effects of oxymetholone include depression , lethargy , headache , swelling , rapid weight gain , priapism , changes in skin color, urination problems, nausea , vomiting , stomach pain (if taken on an empty stomach), loss of appetite , jaundice , breast swelling in men, feeling restless or excited, insomnia , and diarrhea .  In women, side effects also include acne , changes in menstrual periods , voice deepening , hair growth on the chin or chest , pattern hair loss , enlarged clitoris , and changes in sex drive .   Because of its 17α-alkylated structure, oxymetholone is hepatotoxic .  Long term use of the drug can cause a variety of serious ailments, including hepatitis , liver cancer , and cirrhosis ; therefore periodic liver function tests are recommended for those taking oxymetholone. 
There is no clear cause of appendicitis. Fecal material is thought to be one possible cause of obstruction of the appendix. Bacteria, viruses , fungi, and parasites can result in infection, leading to the swelling of the tissues of the appendix wall. The various infecting organisms include Yersinia species, adenovirus , cytomegalovirus, actinomycosis, Mycobacteria species, Histoplasma species, Schistosoma species, pinworms , and Strongyloides stercoralis . Swelling of the tissue from inflammatory bowel disease such as Crohn's disease also may cause appendicitis.
Diet and age are major factors in muscle gain and fat loss. I’m a 45yo male and have to work 5 times harder than 20 somethings to gain muscle and lose fat. when I was 20 something, I was ripped and didn’t have to work hard to get that way and keep it. Then life happened and couldn’t keep lifting and maintaining cadio and other workouts even as much as I did. Now I’m a balding 45yo with a size 38 gut and skinny arms and have been lifting cadio at least 4 to 5 days a week for 6 months. Older equals muscle loss and harder work to couteract it.